

| Introducing a homeopathic treatment for Knee/Muscle Pain |
| Traumeel injection solution, unlike NSAIDs and corticosteroids, is thought to enter the inflammation cascade well before the prostaglandin synthesis begins, thus modulating the inflammation as well as the pain associated with arthritis and other relevant conditions. The protective action of the prostaglandin synthesis remains intact and the healing and repair in joints continues. Zeel injection solution’s multi‐targeted mechanism of action is not fully understood. It is thought that it addresses chronic inflammation, prevention of vascularization of the cartilage and endochondrium, remodeling and protection of cartilage, and alteration to cartilage mechanics. It has an excellent safety profile with very few reported adverse effects, few contraindications and no known drug interactions which makes it suitable for acute and longerterm treatment. It can be safely combined with other treatments but is effective as a monotherapy as well. Traumeel and Zeel injection solutions in combination are indicated for the treatment of inflammatory and degenerative conditions of the musculoskeletal system, such as arthrosis/osteoarthritis and/or rheumatic joint diseases, and for the relief of symptoms including pain, swelling, and joint stiffness. |
| Frequently Asked Questions: Will I feel an immediate reduction in pain? YES – although the most pain reduction is felt after the 3rd weekly Traumeel & Zeel injection. How long do the results last? The duration of pain relief will vary among individuals. In a study published in the ACR in 2014, subjects reported >50% reduction in pain at 3 months that may last longer. Is it possible to make the results last longer? YES – During the 2-3 months after the procedure when your pain is reduced, this is the ideal time to incorporate physical therapy and weight loss to strengthen your muscles and decrease the chronic stress on your joints. Ask Dr Shibuya about an integrative, holistic arthritis approach with less medicine & a healthier lifestyle. Does the treatment hurt? There may be pain during the procedure as the medicine is administered through a small needle, along with local anesthesia. Are there any side effects? Common side effects include local pain, bruising, local swelling, redness or tenderness and numbness or tingling that typically resolves within a few days without treatment. How soon can I return to activity? Patients may return to non-strenuous activity immediately after the procedure. Post-treatment care will focus on anticipated side effects listed above. Consult your physician regarding your specific concerns. |
| What is Traumeel? Traumeel is a special blend of natural plant & mineral extracts, which was developed by Dr Hans-Heinrich Reckeweg, a German physician, in the 1930s, to treat musculoskeletal injuries & inflammation. 60 years & is now available in over 50 countries, including the USA. Traumeel, in combination with Zeel, was found to be effective in treating moderate knee OA pain. |


| When should I call for an appointment? There are many causes of knee pain: bursitis, tendonitis, and osteoarthritis to name a few. 1. If you have had chronic knee pain for >3 months, despite treatments from your MD 2. If you have had side effects to, or have not had a satisfactory response to pain medications, cortisone or knee replacement fluid injections. 3. If you would like to try to AVOID knee surgery or to delay repeat knee surgery. Where can I get more information? You can visit www.MediNatura.com for more information |
| Osteoarthritis of the Knee |

| Fremont Rheumatology Arthritis, Osteoporosis, and Auto-Immune Diseases Barry Shibuya M.D. and Christine Elias M.D. |